Welcome to the precision oncology research lab at City of Hope!
The overarching goal of the Nath lab is to enhance cancer treatment and improve patient outcomes by effectively matching patients with the most suitable treatments. To achieve this, we focus on uncovering the biological mechanisms underlying tumor progression.
Specifically, our research aims to elucidate how tumors evolve during the course of treatment and over time. Through a comprehensive examination of both tumor intrinsic and extrinsic properties, our objective is to gain a holistic understanding of why certain patients experience recurrence and how tumor cells develop resistance to therapies.
Furthermore, we harness this extensive knowledge to construct novel predictive models for patient prognosis and drug responses. We employ cutting-edge computational frameworks to seamlessly integrate complex artificial intelligence algorithms into clinical practice.
Our lab utilizes single-cell and bulk omic data from in vitro models as well as from clinical trials. We integrate experimental approaches with mathematical modeling and computational biology to study tumor evolution and develop predictive models of patient prognosis.
Updates
We are recruiting postdoctoral fellows in computational biology.
